Sunday, January 6, 2008

Metastases to the peripheral nerves

1. These are rare and occur with lymphoma and leukemia. It may be due to spread rather than metastasis per se.

2. Compression of peripheral nerves is much more common, eg. brachial plexopathy and lumbar plexopathy.

3. Hemorrhage into the nerve is another possible mechanism.

4. Presentation can include mononeuropathy multiplex, radiculopathy, mononeuropathy, and polyneuropathy.

5. Paraneoplastic syndromes of the peripheral nerves are described.

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